Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIDFKQDILAPVATDFAAMDHLINEGISSKVGLVMSVSKHVVEAGGKRMRPIMCLLAARACGLDNMQNAQRL--AAIIEMLHTATLVHDDV--VDESGLRRGRPTANATWNNQTAVLVGDFLIARAFDLLVDLN---------NMTLLKDFSTGTCEIAEGEVLQL--QSQHQPDTTEETYLKIIHGKTSRLFELATEGAAILAGQEAYREPLRLFAGHFGNAFQIIDDILDYTSDAETLGKNIGDDLMEGKPTLPLISALAHSTGEEHAIIRRSIATGGVDQLPKVIEIVQKSGALDYCQRRAQEETEAALQALSILPDTPYRQALINLTRLALHRIQ 4LLT Chain:B ((60-265)) --------------------------------------------SGGKRLRGFLVLETAR---LHDIAAGEAIWSATAIEALHAYSLVHDDLPCMDNDDMRRGQPTVHKKWDDATAVLAGDALQTLAFELVTHPGASASAEVRADLALSLARASGAQGMVLGQALDIAAETARAPLSLDEIT-RLQQGKTGALIGWSAQAGARLA--QADTAALKRYAQALGLAFQIADDILDVTGDSAQVGKAVGKDASAGKATF------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4LLT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 791 -1497 -1.89 -7.84 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -1.89 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.250

(partial model without unconserved sides chains): PDB file : Tito_4LLT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LLT-query.scw PDB file : Tito_Scwrl_4LLT.pdb: