Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------------------------------MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVF-----------LDYEKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNG--DFSQQTLPAYKRTNDSLETTIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDV----SAFKERTLEAKYSVIFMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRGLEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSD--RQEICSDFKLVYQASSKEEANNQIRFMIDKWKKQY--PRVVKL--LMNPA----ILTFYNFPPS-----IRRTIYSTNLIEGFNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLC-RVHKGFKEIHDTLESMF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5EHK Chain:A ((4-1114)) DSPFRAWDVFMVRTPVHLSLLRAACEDGLMEAVELASPSLAGLLARVARGDTGGLKDKRLRRAALALLRYDIRMRTRPTPFGLFAGVSGGRFDTSAKWLAGTGHRTRTRADMEWLLSAVHRLERDRVLLAGVTVQAHQTLTVRGDRIVLDCPSALGKSTVSARRSPVVAEILGAARRPVLAGRLAQSVAQRFELPADRVTGLLADMAAQELLITALRPPLDGDDPLQHVLDVVAAAEARAGSPAEAMSSESAALVAALREVDARCHAYDRTAVG-QGRRELAELIQSTRRVHPHDTP----LHVDLRIDLEVRLPEVVRTEIERAAEALWRLSPPRRGMRALRRYHEAFLERYGADRAVPLLELLDDTRGLGPPAGYKWPPSETPAGPQEEPRRSAALARLVAKAARRGEREIVI-DEETIAEL---AYDEAAPADLPNSLELGVHVVAPSLDELSAGTFRVVLAPGPGSHHAGATLGRFTGLLPDVDAESAARQAGRPLHIQDAVAADVAFIPRSGRAANLAHTPSYSGRRISVGLPDSGRAQEIPLDELGVGANLERLCLVHLPTGREVVPALPNMVSAFAQAPNPARLLFELGLEGQRLWEPWDWGALSEMPFLPGVRYGRTLLAAPLWRMDQLRGPADDSGPAADWDAALDRWRAEWNVPRRVLAVSMDQRLLLDLDDAWHRVLLRDELRRTPELIAQQVAGDEEGWLDFPGHLAEIVVPLERRDRHAARPPHIRATVSPTGAGGPWLYLRLRVPRRNQDDFLRDQVPVLVRAGIEHGADRWFFIRYSDTAGQHLRVRFRGEREKLWAGLLPEIGARLVEWQRQGLLAGHELGQYDPEYERYGGDALAEFTETAFQHDSAAAISLLRLTRRAGFRYTLDEVTAISAAALADAFGPPAPVVEPVPLVGGLQWAPDLFDGDPAAAWMSSTGGRRELPPDYRRDPARWQKLIDPTGGWPLLRADEDGCQVLAALESRDEAVRRFGTAYREAFRPTDSPSTQLRLVGSLLHMTCNRLIGGSAERERSVLGLARGAVQDNLNRRRH

General information: TITO was launched using: RESULT: Template: 5EHK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1564 6566 4.20 17.28 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 4.20 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.257

(partial model without unconserved sides chains): PDB file : Tito_5EHK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5EHK-query.scw PDB file : Tito_Scwrl_5EHK.pdb: