Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSATGLTGSGSRDWFIQRVSAVVLAAYTVVLFGWIL--CKGGFDYQQWAGFMMTLPMKIFSLLAILSLIAHAWIGMWQVFTDYVTTRQMGP-SAKGLRLVLTTAVIIAVFVYAIWGIQIFWAN 2WDQ Chain:C ((20-126)) -------FPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGY----LEETFEAGKRSAKISFVITVVLSLLAGV------

General information: TITO was launched using: RESULT: Template: 2WDQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 243 -40478 -166.58 -389.21 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain C : 0.73 3D Compatibility (PKB) : -166.58 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.221

(partial model without unconserved sides chains): PDB file : Tito_2WDQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WDQ-query.scw PDB file : Tito_Scwrl_2WDQ.pdb: