Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLG---GFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLE--TAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKF----EGEGAAVRTS----AEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK 3QTP Chain:B ((8-429)) ---IQKVHAREILDSRGNPTIEVEITTGKGMF-RSCVPSGASTGVHEAVELRDGDKKRYGGKGVLKAVENVNTIIGPALLGKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICRAAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHEALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYT-GK-IEIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKH----YPIASIEDPFAEDDWAAWNKFTVEHG-NFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETFKTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIEEELGNI--------------

General information: TITO was launched using: RESULT: Template: 3QTP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2569 -7087 -2.76 -17.33 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.85 3D Compatibility (PKB) : -2.76 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.563

(partial model without unconserved sides chains): PDB file : Tito_3QTP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QTP-query.scw PDB file : Tito_Scwrl_3QTP.pdb: