Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHPIVIIGSGMAGYTLAREFRKLNPEQELVMICADDAVNYAKPTLSNAFAGKKAP-EQIPLGDAAKMSAQLNMRIEPFTWVKEILAERHELVLEKD--GIISQQPYSKLILAVGANPIRLAIAGDG-SDDIHVVNSLIDYRSFRENLAQRKDKRVVILGAGLIGCEFANDLLHSEYDVTVIDLAPQPLGRLLPSHIASAFQQNLEEAGVKFTLGTTVEKVSKINNGEDYAVTLANGQTLVADIVLSAIGLQPNISLAQSANIQTS--RGVITNSLLETNQADIYAIGDCAEVNGT------LLPYVMPIMQQARALAKTLSGQQ-TNVHYPAMPVAVKTPAAPLTVLPAPVDVDVN----W---ETE---------EFDDGM-LAKAIDNEGTLRGFVLLGATAGKQRLTLTKLVPDLIPAQA 3ICT Chain:A ((36-446)) SRKIVVVGGVAGGASVAARLRRLSEEDEIIMVERGEYISFANCGLPYYIGGVITERQKLLVQTVERMSKRFNLDIRVLSEVVKINKEEKTITIKNVTTNETYNEAYDVLILSPGAKPIVPSIPGIEEAKALFTLRNVPDTDRIKAYIDEKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMPPID-YEMAAYVHEHMKNHDVELVFEDGVDALEEN----GAVVRLKSGSVIQTDMLILAIGVQPESSLAKGAGLALGVRGTIKVNEKFQTSDPHIYAIGDAIEVKDFVTETETMIPLAWPANRQGRMLADIIHGHTDSLYKGTLGTSVAKVFDLTVATTGLNEKILKRLNIPYEVVHVQANSHAGYYPNATPVLIKLIFNKDSGKIYGAQTLGRDGVDKRMDVIATAI-------

General information: TITO was launched using: RESULT: Template: 3ICT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2097 -38237 -18.23 -100.36 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -18.23 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.503

(partial model without unconserved sides chains): PDB file : Tito_3ICT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ICT-query.scw PDB file : Tito_Scwrl_3ICT.pdb: