Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKHQRPTNELPQGGIIEKEAAIHVSNVQVLD-KNGVAGRVGYKFVDGKKVRYNKKSGEVLD 5DM7 Chain:R ((14-112)) LHFKKGDTVIVLSGKHKGQTGKVLLALPRDQKVVVEGVNVITKNVKPSMTNPQGGQEQRELALHASKVALVDPETGKATRVRKQIVDGKKVRVAVASGK---

General information: TITO was launched using: RESULT: Template: 5DM7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain R - contact count / total energy / energy per contact / energy per residue : 350 -8659 -24.74 -88.36 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain R : 0.79 3D Compatibility (PKB) : -24.74 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.384

(partial model without unconserved sides chains): PDB file : Tito_5DM7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DM7-query.scw PDB file : Tito_Scwrl_5DM7.pdb: