Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMTYTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQ------------EIMADTDIVHMTKTDVAVVSPDFTITEVLHKLVDES--FLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ 3SL7 Chain:B ((3-161)) ----------GYTVGDFMTPRQNLHVVKPSTSVDDALELLVEKKVTGLPVIDDNWTLVGVVSDYDLLAL--------TWKTFNELQKLISKTYGKVVGDLMTPSPLVVRDSTNLEDAARLLLETKFRRLPVVDADGKLIGILTRGNVVRAALQIKRNA---------

General information: TITO was launched using: RESULT: Template: 3SL7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 583 -36293 -62.25 -288.04 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -62.25 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_3SL7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SL7-query.scw PDB file : Tito_Scwrl_3SL7.pdb: