Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSFTRINGVLHAEQCSLEQLAQQFGTPLYVYSKAAFEKHYLDMDRAFDFIDHQICFAVKSNSNIAVLNVLAKLGAGFDIVSGGELARVLKAGGD----ASKIVFSGLGKTEADIETSLNVGIACFNVESYAELDRIQKVAARLGKKAPISLRVNPDVDAKTHPYISTGLKENKFGIPSDAVYETYQYAASLPNLEIVGIDCHIGSQLTETKPFVDALDRVIVMIDELKKLGINLKHIDIGGGLGVCYKDET-PP---SVEEYANSMKPALEK---LGLKVYMEPGRSISANAGVLLTKVDLLKPTTHRNFAIIDAAMNDLIRPALYEAWMDIQPV--VPR--TDTEEKTWDLVGAICETGDFIGKD-------RSLA-LQENDLLTVLGAGAYGFVMSSNYNTRGRAAEVMVSGEKSYLIRERETVESLWEKERLLPEE 1KNW Chain:A ((2-420)) -PHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALKQ-FD----VVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTADVIDQATLERVSELQI-PVNAGSVDMLDQLGQV----SPGHRVWLRVNPGFGHGHSQKTNTGGENSKHGIWYTDLPAALDVIQ-RHHLQLVGIHMHIGSGV-DYAHLEQVCGAMVR---QVIEFGQDLQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVETVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNGQARLIRRRQTIEELLALELL----

General information: TITO was launched using: RESULT: Template: 1KNW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2330 -47715 -20.48 -120.49 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -20.48 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_1KNW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KNW-query.scw PDB file : Tito_Scwrl_1KNW.pdb: