TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

--------------------------------------------------------------------MLVTMENYQIIESIGEGSFGKVYKARIKGTGQIVAMKFIVKKGKNEKELKN-LRSEIEILTKLNHPHIIMLFDSFETDSDFVVVMEYAQ-GELYDILED-EKQLPAKEVQKIAKQLIQALNYLHSNRIIHRDMKPQNILIGQNGAVKLADFGFARSMSYNTIVLTSIK-GTPLYMAPELVQERA-----YDNRVDLWSLGCILYELYYGKPPFYTNNLFALIKKIVCEPVKYD-SKANDPISPEFKSFLSGLLTKSASSRL---NWPELLNHPFVQ------LTKSDASWQDAIMQHDSRMKARMDRLGCLRLHG---NAGRAAPKRKSTQSDDIFNLKTVQKLTSGCEFDVCATLTQLVRMARASNGDVTKSTALLGVFDSGVLEAALTLLNEKQSVKVVGLVLQFVQELVFPEHGDLLAFPSQRPKRDGLAVLEEKHSRQQEDLFIRQQVALKLMKKPHTALDFIISEISSGGDSLAETCVKIMFQCFRWENSFGPMVTQLRTFPEMWAAILKSVNHHSVSRGETSHEYAALVFHTVSIVIPHVKLASPQRINREEVLELVTQGLSAVCYYEAGMVDAHRNKTPPLVYAAAAALLIAFAHRELKDIVSFKVNGALLDGIYSIVDAVTDAPSRPVTPRALGSSYGYPDYGLLDGVAHMLSLVFSDSDSLVYAKLPGRSEHRFLESDTKSLALLVMTLLRDSDPRMELSPNGVQTLLRAAQQIFQQEKEQALSMSLLMEPIAPYSGESGSLCWLSVICRTMKTDYFRQLFYWPACRGGGATGVSAHVTIVSQILSDSLRPVSSSSNPTPVEDKLLGDVSRVLYKEKVIELLVHAMDYSEGVFLGSPFAIIAKLCANSADSIKAFVDCGGVDAARIRRILDPDKAGTGLMSDGLVVLSQMARMSAEFYEPIHRSNLYDCLAALLQHSEKDLRGKTCTLIGNLCKHSDFFFEPLEKNHIVERLVKCCSDSDAQTQKLAAFAIGNAAFHSGYLYNLLSPAIPSLVGLLACGDAKTRQNAAGALSNFVRNGDQLVSSLAESSVVESLLKMLRDDDTPSSKKVAVLTINSFCAYDVFRRKFIALNLREDIRKLQQDPNARADPSIQKYVGNLVDRLG

4AW2 Chain:A ((1-416))

SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEGGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLIC-SREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDSGHHLPFVGFTYTSSCVLSDRSCLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information:

TITO was launched using:	RESULT:
Template: 4AW2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1288 12785 9.93 41.51 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : 9.93 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.457

(partial model without unconserved sides chains):
PDB file : Tito_4AW2.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-4AW2-query.scw
PDB file : Tito_Scwrl_4AW2.pdb: