Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGPRPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQ-LDIPVLGVILPGASAAIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSVTKKVVYETLRPLVG-KVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLLNYFEINRGRD---AGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL 5IJW Chain:A ((5-266)) DRLAPIGIFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPQIRAHSLAIGDDLVSRGVKALVIACNTASSACLRDARERYSPVPVVEVILPAVRRAVAATRNGRIGVIGTQATIASGAYQDAFAAAR-DTEVFTVACPRFVDFVERGVTSGRQVLGLAEGYLEPLQLAEVDTLVLGCTHYPMLSGLIQLAMGDNVTLVSSAEETAKDLLRVLTELDLLRPHPDDPSVTAVRRFEATGDPEAFTALAARFLGPTLD------

General information: TITO was launched using: RESULT: Template: 5IJW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1499 -81478 -54.35 -317.03 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -54.35 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.590

(partial model without unconserved sides chains): PDB file : Tito_5IJW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IJW-query.scw PDB file : Tito_Scwrl_5IJW.pdb: