Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVYYPQPVDNLVNKRSCKRRRYITMKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEGA--QKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNLDKL-GT-----E-AELNYL--Q-------HGDPSGTIFSIGEADVSIRPGWFYHEDQ--DPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERPYEFATYRNELYKEDLALGAEVSGPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKTPGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSRSS----------SSL-EAKISIQPGTGVHGVA-----Y---QDEIYALAFQAGETEKRLTLP---TLYFA-GDKTLDFYLNLTVDGQLVDQLQVQVS 4ZRX Chain:A ((26-580)) ----------------------------MAARLVPTPQQYAWQQMELTAFLHFGINTFTGREWGDGKEDPALFNPSELDAEQWVRTLKEAGFKMVLLTAKHHDGFCLWPTATTKHSVASSPWKNGQGDVVKELRAACDKYDMKFGVYLSPWDRNAECYG--DSPRYNDFFIRQLTELLTN-----YGEVHEVWFDGANGEGPNGKKQVYDWDAFYQTIQRLQPKAVMAI-MGDDVRWVGNEKGVGRETEWNATVLTPGIYARSQENNKRLGVFSKAEDLGSRKILEKATELFWYPSEVDVSIRPGWFYHAEEDGKVKSLKHLSDIYFQSVGYNSVLLLNIPPDRRGLIHEADIKRLKEFADYRQQTFADNRVKN---------------------GRKYWSTTS--GGEAVYALKSKSEINLVMLQEDITKGQRVEAFTVEALTDNGWKEVGKGTTIGYKRMLRFPAVNANKLRVRIDECRLTAYVSQVAAYYAEPLQEETTKE------------DWNNLPRSGWKQVAASPLTIDLGKTVTLSSFTYAPSKAEVKPTMAFRYQFFVSMDGKSWKEVPASGEFSNIMHNPLPQTVAFSQKVQARFIKLEATTPDATVAKVNMNEI

General information: TITO was launched using: RESULT: Template: 4ZRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2798 23960 8.56 46.80 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 8.56 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.415

(partial model without unconserved sides chains): PDB file : Tito_4ZRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZRX-query.scw PDB file : Tito_Scwrl_4ZRX.pdb: