Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDTDPLVSCENLTSIVNLEHLMTTPVSFHPQAFIELALSRGVLKFGEFTLKSGRVSPYFFNAGLLNDGEALSLLAQGYADKLTQ-CENVDVIFGPAYKGIPFVAATAVALSQTHNKSVPWGFNRKEAKDHGEGGVLVGAAVEGKKVWIIDDVITAGTAIREVVTILKNAGATIAGVLVALDRQERGQGELS-AIQEVQKELEIPVHALITMKDLMDYLEAKGE-KEALANMQAYREKYGI 1LH0 Chain:B ((3-213)) ---------------------------PYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKE-------GSLVGSA-LQGRVMLVDDVITAGTAIRESMEIIQAHGATLAGVLISLDRQERGRGEISAIQEVE-RDYGCKVISIITLKDLIAYLEEKPDMAEHLAAVRAYREEFGV

General information: TITO was launched using: RESULT: Template: 1LH0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1034 -58289 -56.37 -290.00 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -56.37 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.644

(partial model without unconserved sides chains): PDB file : Tito_1LH0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LH0-query.scw PDB file : Tito_Scwrl_1LH0.pdb: