Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIDFKQDILAPVATDFAAMDHLINEGISSKVGLVMSVSKHVVEAGGKRMRPIMCLLAARACGLDNMQNAQRL--AAIIEMLHTATLVHDDV--VDESGLRRGRPTANATWNNQTAVLVGDFLIARAFDLLVDLN---------NMTLLKDFSTGTCEIAEGEVLQL--QSQHQPDTTEETYLKIIHGKTSRLFELATEGAAILAGQEAYREPLRLFAGHFGNAFQIIDDILDYTSDAETLGKNIGDDLMEGKPTLPLISALAHSTGEEHAIIRRSIATGGVDQLPKVIEIVQKSGALDYCQRRAQEETEAALQALSILPDTPYRQALINLTRLALHRIQ 4LLS Chain:B ((60-265)) --------------------------------------------SGGKRLRGFLVLETAR---LHDIAAGEAIWSATAIEALHAYSLVHDDLPCMDNDDMRRGQPTVHKKWDDATAVLAGDALQTLAFELVTHPGASASAEVRADLALSLARASGAQGMVLGQALDIAAETARAPLSLDEIT-RLQQGKTGALIGWSAQAGARLA--QADTAALKRYAQALGLAFQIADDILDVTGDSAQVGKAVGKDASAGKATF------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4LLS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 793 -3676 -4.63 -19.24 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -4.63 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_4LLS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LLS-query.scw PDB file : Tito_Scwrl_4LLS.pdb: