Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIALFSKNWSRTMSATIVNTTDDNFQADVLDAETPVLVDFWAGWCAPCKAIAPVLEDLSSEYAGKVKIVKVDVTSCEETAVKYNIRNIPALLLFKNGEVVAQQIGAVPRSKLVSFIDENV 2H70 Chain:B ((2-107)) ---------------DKIIHLTEDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANL

General information: TITO was launched using: RESULT: Template: 2H70.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 465 -90754 -195.17 -856.17 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain B : 0.82 3D Compatibility (PKB) : -195.17 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.792

(partial model without unconserved sides chains): PDB file : Tito_2H70.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H70-query.scw PDB file : Tito_Scwrl_2H70.pdb: