Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTKSAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGSALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGKGPFTIELFG-GSPDDNNALINYNGVMSVLQPYMDNG-----------------------QLVVPSGQTSFSQIATLRWDGSTAQARMDNLLSANY-TDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATVAGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYLANTVSVDKDNYQAELIDTDYYKESDLKN 4RXU Chain:A ((28-363)) -------------------------------TQQLAVGIVLPTKDEPRWIQDETRFREALQQAGYQVEILFSQGSSAKEKENVEALIAKGIKVLIICPHDGTAAAAAAEAARAAGVKVISYDRLIRETDAVDYYVTFDSIAVGAQQAQYLVDHASG-----TGNPLYLYAGAASDNNAFLFFEGAWKVLQPKIADGTFVIKNSSEAVALQNKLDLTRDEMAKIIGQ-------VTTNWDFNTAKNLAEANLTAATAADKGKVYILAPNDGTARAIADAFAADKDV---TE-YFVTGQDAEKASVQYIIDGRQSMTVFKDVRTLVQDAIKAAVALLQDQQPEAR--GTYNNGKKDVPAIQSPVVTVTRDNVRAALIDSGYYSASDF--

General information: TITO was launched using: RESULT: Template: 4RXU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1876 -49500 -26.39 -159.16 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -26.39 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_4RXU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RXU-query.scw PDB file : Tito_Scwrl_4RXU.pdb: