Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTQNLMCPVCRQRLELVSKTWRCEQGHSYDIAKQGYVNLHVVQHKHSKNPGDTPESVDARRAFLQGGYYQPLQQAVVHLLKDLQAKMVLDIGCGEGYYTSAMQQVVEQCIGVDIAKNAVQRAAKLNDKVTWVVGTGATLPVIDQSMDVCTSLFS-------PIPQTEILRVVKDDGYLIVVTSATDHLYAMREALF--------EQ------VNPHIPQKFVEQLQ-DLFELKEQQVIDAPLVLDQ--QALKNLIAM--TPYAYKASPERRMQLEQ------------KAHLQVTASFQIYLFQKRNKKAI 3CCF Chain:B ((47-279)) --------------------------------------------------------------------------EDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGTDNAATMIEKARQNYPHLHFDVADARNFRV-DKPLDAVFSNAMLHWVKEPEAAIASIHQALKSGGRFVAEFGGKGNIKYILEALYNALETLGIHNPQALNPWYFPSIGEYVNILEKQGFDVTYAALFNRPTTLAEGEFGMANWIQMFASAFLVGLTPDQQVQLIRKVEATLQDKLYHQESWTADYRRIRIVSIKAQ----

General information: TITO was launched using: RESULT: Template: 3CCF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 840 -63925 -76.10 -327.82 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -76.10 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3CCF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CCF-query.scw PDB file : Tito_Scwrl_3CCF.pdb: