Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CLGVLLRNDGRKPILGFEPFRIRRTVSFPGYDFVLKVGRRCITEKISGTIPPHLHVHVVWGFPAPVRPVCN--VYNGWTERFER---YGRNVREAPW 1VCC Chain:? ((1-77)) -MRALFYKDGK--LFTDNNFLNPVSDDNPAYEVLQHV-----------KIPTHLTDVVVYE--QTWEEALTRLIFVGSDSKGRRQYFYGKMHV----

General information: TITO was launched using: RESULT: Template: 1VCC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 275 -30708 -111.67 -426.50 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -111.67 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.381

(partial model without unconserved sides chains): PDB file : Tito_1VCC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VCC-query.scw PDB file : Tito_Scwrl_1VCC.pdb: