Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVD---QGEKPLLEGDFRFLQRDLTLDLEPI------FDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVELTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGIQVFGIAPGAVKT--AMTAADFEPG---GLADWVASETPIKRWIEPEEIAELSLFLASGKASAMQGQILTIDGGWSLK 2D1Y Chain:C ((7-246)) --KGVLVTGGARGIGRAIAQAFAREGALVALCDLRPEGKEVAEAIGGAFFQVDLEDERERVRFVEEAAYALGRVDVLVNNAAIAAPGSALTVRL-PEWRRVLEVNLTAPMHLSALAAREMRKVGGGAIVNVASVQGLFAEQENAAYNASKGGLVNLTRSLALDLAPLRIRVNAVAPGAIATEAVLEAIALSPDPERTRRDW-EDLHALRRLGKPEEVAEAVLFLASEKASFITGAILPVDGGMT--

General information: TITO was launched using: RESULT: Template: 2D1Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1241 -33057 -26.64 -146.27 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain C : 0.76 3D Compatibility (PKB) : -26.64 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_2D1Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D1Y-query.scw PDB file : Tito_Scwrl_2D1Y.pdb: