Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------MTKRVTIIDVKDYVGQ-EVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDER---SKFGYELDITDIEVIG-------------ESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFMKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMA-LGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLT-HDESLDLQEAYVKALLQGVLDRAPQALETLERDTEL--LKRYIAEPFKRITYDQAIDLLQ--EHENDEDADYEHLEH------GDDFGSPHETWISNHFGV-----PTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDR-----TEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP 1B8A Chain:A ((1-438)) MYRTHYSSEIT-------E-ELNG-QKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPK--------KKVDPELFKLIPKLRSEDVVAVEGVVNFTP-KAK--LGFEILPEKIVVLNRAETPLPLDPTGK---------VKAELDTRLNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKYFEEDAFLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDEEEVMSFLERLVAHAINYVREHNAKELDILN--FELEEPKL----PFPRVSYDKALEILGDL---------------GKEIPWGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEY--RGVEISSGGQREHRHDILVEQIKEK----GLNPE-SFEFYLKAFRYGMPPHGGFGLGAERLIKQMLDLPNIREVILFPRDRRRLTP

General information: TITO was launched using: RESULT: Template: 1B8A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1737 67401 38.80 172.82 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 38.80 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.339

(partial model without unconserved sides chains): PDB file : Tito_1B8A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B8A-query.scw PDB file : Tito_Scwrl_1B8A.pdb: