Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVTTYIGLGSNLGDSRQILSEAITKLKSLGEV------KVSKLYQSPPMGPQDQPNYLNAVAQLKTELLPLELLDQLQRFEQEAGRVR-LRHWGERTLDLDLLIYGNEKIQNERLTVPHVGILQRDFVVIPLLDLDADLHINDQPLKNLELIQQPTLTVLADESWA 1TMM Chain:B ((1-139)) --TVAYIAIGSNLASP---LEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERAGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPD-----------------------

General information: TITO was launched using: RESULT: Template: 1TMM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 647 17972 27.78 136.15 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : 27.78 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.456

(partial model without unconserved sides chains): PDB file : Tito_1TMM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TMM-query.scw PDB file : Tito_Scwrl_1TMM.pdb: