Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDGAMQGSYATALLKQQQLPESFQFYFKQKQHLSNTQELHQLHELVRPRLKIAIVTETWPP--EINGVALSLLQLCQGLQKQGHKILLVRPEQKAKCHD----------------------FLPE-QECLVMSQAIP-----KY---------PTL-QFG---WPQYLKVSKAFEKFVPDVVHIVTEGPLGLTAMQAAKAKDIPVSSGFHSPFQDFSRFF---D---LAF--------LVKPIQKYLCWFHNNTQVTCVPSKDTEEALRGF----G--------ITC-PLVVVGRGVDTTRFSPKHRS------------------ENLRQQWGV--DSDTRVMLYVGRLSPEKEVQLIVESYAAMQNIQQQKTKLVVVGDGPD--LARLKALPEAK--NV-IFTGSLCGHDLAVAYASADVFVFASQVETFGNVVLEAMASGLPVIAYDYACAHQYLIHG---------VNGWLSPLGHKNHFIQQIYQLP---S-IQQLREMGIQACHKVQQSGWQLPVQQLEQAFYQVVKELSADFT 2QZS Chain:A ((1-477)) -------------------------------------------------MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQ---GGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYH-EAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQA--MAMDFSWQVAAKSYRELYYRLK--------

General information: TITO was launched using: RESULT: Template: 2QZS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2002 -36287 -18.13 -98.34 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -18.13 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.425

(partial model without unconserved sides chains): PDB file : Tito_2QZS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QZS-query.scw PDB file : Tito_Scwrl_2QZS.pdb: