Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNLYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSANGETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTY-DLKQAMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYAYESDPVSIFGGIAVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFTGVRHFRH 1ZCZ Chain:B ((13-464)) -MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGILG--------------PEPRWDVVFVDLYPP---------------PDIDIGGVALLRAAAKNWKKVKPAFDMETLKLAIEI------DDEETRKYLAGMTFAFTSVYDSIRANQFVEGI--------SLAFKREDLQLRYGENPHEKAFVYGK-P------AFEILHEGKTISFNNILDAENAWFMAKNLPR-MGAVVVKHQSPCGAAIGEDKVEIVKKAIEADDESSFGGILAVNFEMDEEVAKSL-KKYLEVIVAPSFTQEAIEVLSKK--KVRLLKPGD-YA-----SWAGKMAFGSLVLSERKYPEG---NFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLIAKDGVTVGIGSGQPSRKRAAWIATVMAGEKAKGAVAASDAFFPFPDSLEILAQAGVKAVVAPLGSIRDEEVIEKARELGITFYKAPSRVFRH

General information: TITO was launched using: RESULT: Template: 1ZCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2385 -127230 -53.35 -282.11 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -53.35 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_1ZCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZCZ-query.scw PDB file : Tito_Scwrl_1ZCZ.pdb: