Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIEIKRIQQQPDLAQDIYAVMAAVYPV----SPWTLEQIQADLSQ---DQTWYALAYDGAEVIGFLTVQET---LFEAEVLQIAVKGAYQGQGIASALFA-----Q-LPTDKEIFLEVRQ--SNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG 2R7H Chain:B ((21-176)) -AFRRQV--LPQDALLVRRVVESTGFFTPEEADVAQELVDEHLMHGAACGYHFVFATEDDDMAGYACYGPTPATEGTYDLYWIAVAPHRQHSGLGRALLAEVVHDVRLTGGRLLFAETSGIRKYAPTRRFYERAGFSAEAVLKAFYRAG-DDKIIYRLEV---

General information: TITO was launched using: RESULT: Template: 2R7H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 568 -8337 -14.68 -60.41 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : -14.68 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_2R7H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2R7H-query.scw PDB file : Tito_Scwrl_2R7H.pdb: