Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDASDF--LEADIAIVATYTYGDGELPDEMMDFYEDLADL--NLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG 4OXX Chain:A ((1-148)) -MNALILYGTETGNAEACATTISQVLAD-TVDTKVHDLADMTPRAMLDSGADLIVFATATYGEGEFAGGGAAFFETLRETKPDLSGLRFAVFGLGDSYYTTFNQAGATAATILASLGGTQVGDTARHDTSSGDDPAATAAEWAREILTAL-

General information: TITO was launched using: RESULT: Template: 4OXX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 822 -44241 -53.82 -307.23 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -53.82 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_4OXX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OXX-query.scw PDB file : Tito_Scwrl_4OXX.pdb: