Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKSVTQENSVPVIGQRFRGFLPVVVDVETAGFNAQTDALLEIACIPIVYDAQGQFVPGPAFHAHINPFEGANLDRRSLDFIGIDPFNPM-RIAMAEDERTALRRIFKSVNEVRKQQHCTHAVLVGHNAHFDLGFLQAAIARSGTKNQNPFHSFSVMDTVTLSAVMFGQTVLAKACIQAGIEFDGKEAHSALYDTQKTAELFCYILNKLSPYLLDSLVAAS 3V9W Chain:D ((26-232)) ---------QLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDP-NDPDRGAV--SGYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRN-PFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAA-

General information: TITO was launched using: RESULT: Template: 3V9W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1066 -87415 -82.00 -424.34 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain D : 0.85 3D Compatibility (PKB) : -82.00 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_3V9W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V9W-query.scw PDB file : Tito_Scwrl_3V9W.pdb: