Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATPFWYNTALHLLKPFYRWRIKRRAESLELYQQECLERFGPFEAPKNVKAIWFHAVSVGETNAAQPLIEYYLKL--GQPVLVTNTTKTGQARAKSLFLKEPYLDLFQ-AV---YLP--------VDQKPLLKKFFELYQPKLLALVETELWPNL-IDQAKLQHVPCLLLNARLSEKSAK-GYGKVSGLTAGMLKQLDWVLAQDSATRQRYVELGLDEHKSQVVGNIKFDIHAPEAFIKQAAQLRQQWYLE-N-RQVVTIASTHA-P-EEQQILEAFAPYLNSDRELVCIVVPRHPERFDEVFEICQN-LNLITHRRSMGQSIHASTQVYLADSM--GELWLWYALSQVCFVGGSLNEPGGGHNILEPMVLNVPTVVGPRYFNFQTIVDEFIDENAVLIAQDAQQVVDIWLACLAEPEATEQLVAQAHKVLQRNQGSLQKHIGVINRYLAEKS 3OT5 Chain:B ((25-393)) ----------------------------------------------MAKIKVMSIFGTRPEAIKMAPLVLALEKEPETFESTVVITAQHREML-DQVLE-I---FDIKPDIDLDIMKGQTLAEITSRVMNGINEVIAAENPDIVLVHGDTTTSFAAGLATFYQQKMLGHVEAGLRTWNKYSPF-PEEMNRQLTGVMADIHFSPTKQAKENLLAEGKDPATIFVTGNTAIDALKTTVQKDYHHPILE--NLGDNRLILMTAHRRENLGEPMQGMFEAVREIVESREDTELVYPMHLNPA---VREKAMAILGG-------------HERIHLIEPLDAIDFHNFLRKSYLVFTDS-------GGVQEEAPGMGVPVLVLRDTTERPEGIEA-GTLK--LIGTNKENLIKEALDLLDNKESHDKMAQAANPYGD--GFAANRILAAIKSHFE---

General information: TITO was launched using: RESULT: Template: 3OT5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1956 37441 19.14 108.52 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.61 3D Compatibility (PKB) : 19.14 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.407

(partial model without unconserved sides chains): PDB file : Tito_3OT5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OT5-query.scw PDB file : Tito_Scwrl_3OT5.pdb: