Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQTLHVELGERRYPIFIGSQL--D-PKQ-LLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGK------TVATCILPDGEKYKDIQHLNLIFDALLEAG--FNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVAR--------------DADLLAEAVYRSCAHKARIVANDEKEQGERALLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQI-----------PLDDFLGHMAHDKKVLNGQLRLVLLKQLGQAVITK--DFDVELMKQAILANQHG 1NVB Chain:B ((10-391)) ---------LGRESIIADFGLWRNYVAKDLISDC-SSTTYVLVTDTNIGSIYTPSFEEAFRKRAAEITPSPRLLIYNRPPGEVSKSRQTKADIEDWMLSQNPPCGRDTVVIALGGGVIGDLTGFVASTYMRGVRYVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPTKIYIDLEFLETLPVREFINGMAEVIKTAAISSEEEFTALEENAETILKAVRREVTPGEHRFEGTEEILKARILASARHKAYVVSADEREGGLRNLLNWGHSIGHAIEAILTP-QILHGECVAIGMVKEAELARHLGILKGVAVSRIVKCLAAYGLPTSLKDARIRKLTAGKHCSVDQLMFNMALDKKNDGPKKKIVLLSAIGTPYETRASVVANEDIRVVL------

General information: TITO was launched using: RESULT: Template: 1NVB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1817 -29940 -16.48 -87.29 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -16.48 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_1NVB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1NVB-query.scw PDB file : Tito_Scwrl_1NVB.pdb: