Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLSIGQLSKKADVPIDTIRYYEKVGVLDRIQRSENNYRVYTDQTLADLLFIKHCRELDISLSDIKTLKEMKAQPKRACTEVDNLVNKYLIEVSEKIERLLLLKETLIDLKQHCSTDRTVDECGILKELQNHP 4UA1 Chain:B ((3-130)) --FRIGELADKCGVNKETIRYYERLGLIPEPE--EKGYRM--QQTVDRLHFIKRMQELGFTLNEIDKLLGVVDRDEAKCRDMYDFTILKIEDIQRKIEDLKRIERMLMDLKERCPENKDIYECPIIETLM---

General information: TITO was launched using: RESULT: Template: 4UA1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 299 -18885 -63.16 -152.30 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -63.16 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_4UA1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UA1-query.scw PDB file : Tito_Scwrl_4UA1.pdb: