Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAELNTPLTVGDFEIKNRLVMAPLTRARSGESRVPNDLMVEYYQQRA-NAGLILTEATVIGSKTVGYADTPGLWSQEQAQAWNKIIEAVHAQGSKIVVQLWHVGRISHPELL-DGDIPVA-------PSAIQPAGEVSLLRPKRPYVTPRALSIEEIQEIVAQYKHSAELAKAAGFDGVELHAANGYLIDQFLQSNTNQRDDEYGGPVENRARLLLEVVDAFIEVWGAGRVGVHIAPRGDSHDMGDENPLATFGYVVEQLSQRNVAFIFSRE--YEAADSISPQLRKKFNGVWIANENLTPESAKRILREGQADAVSFGKAYIANPDLLQRLEQGLPLNELQPTTLYAKG-AEGYTDYPALEAS 3HGR Chain:A ((16-373)) ---LMSPCKMGKFELCHRVVLAPLTRQRS-YGYIPQPHAILHYSQRSTNGGLLIGEATVISETGIGYKDVPGIWTKEQVEAWKPIVDAVHAKGGIFFCQIWHVGRVSNKDFQPNGEDPISCTDRGLTPQIMSNGIDIA------HFTRPRRLTTDEIPQIVNEFRVAARNAIEAGFDGVEIHGAHGYLIDQFMKDQVNDRSDKYGGSLENRCRFALEIVEAVANEIGSDRVGIRISPFAHYNEAGDTNPTALGLYMVESLNKYDLAYCHVVEPR---TESLVP-MRKAYKGTFIVAGGYDREDGNRALIEDRADLVAYGRLFISNPDLPKRFELNAPLNKYNRDTFYTSDPIVGYTDYPFLE--

General information: TITO was launched using: RESULT: Template: 3HGR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2058 30696 14.92 91.36 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : 14.92 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.619

(partial model without unconserved sides chains): PDB file : Tito_3HGR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HGR-query.scw PDB file : Tito_Scwrl_3HGR.pdb: