Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMNKQPQNSALVVVDVQNGF-TPGGNLAVADADTIIPTINQLAGCFEN----VVLTQDWHPDNHISFAANHPGKQPFETIELD--------YGSQVLWPKHCIQGTHDAEFHPDLNIPTAQ---LIIRKGFHAHIDSYSAFMEADHTTMTGLTGYLKERGIDTVYVVGIATDFCVAWTALDAVKQGFKTLVIEDACKGIDLN-GSLEQAWQTMQQQGVIRIQSTDLLNEC 2H0R Chain:A ((1-216)) --------MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK-------

General information: TITO was launched using: RESULT: Template: 2H0R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1082 32229 29.79 161.95 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 29.79 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.518

(partial model without unconserved sides chains): PDB file : Tito_2H0R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H0R-query.scw PDB file : Tito_Scwrl_2H0R.pdb: