Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLKMRLKHIILTTCLCSTLAMAELPQDSRRPGGIAVIPLTSDITQVTFQHKPVLISQEGQQRYAVFGIPLSTPLGSVQLETNKAPIQIEVKSYPYAEQRLKVTNQDYVNPNQSQLDRYAQEAKEQNDVYSSFTQSSWQALPKFIRPTSGKFTNSFGRKRFFNGEERAPHSGLDIPAPIGQKVVAPADGVVVQTGHYFFNGQTVLIDHGQGLISMFCHLSEIRVEKGQHIRQGETLGLVGKTGRVTGPHLHWGMSLNNARVDPQLFLTTTH 4BH5 Chain:C ((16-141)) ------------------------------------------------------------------------------------------------------------------------------------------APRGQAFWPVRGPTLHRYGEQLQG----ELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLG---

General information: TITO was launched using: RESULT: Template: 4BH5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 666 -67844 -101.87 -538.44 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain C : 0.61 3D Compatibility (PKB) : -101.87 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_4BH5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BH5-query.scw PDB file : Tito_Scwrl_4BH5.pdb: