Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------DCIISRYKDGDVNNMYTANRNEEITIEEYKVFVNEACHPYPVILPDRSVLSGDFTSAYADDDESC--- 1I8T Chain:A ((245-313)) EYRSLKFETERHEFPNFQGNAVINFTDANVP--YT-----RII--EHKHF-----DYVE---TKHTVVTKEYPLEWKVGDEPYYPV

General information: TITO was launched using: RESULT: Template: 1I8T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 86 -1666 -19.37 -34.70 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -19.37 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_1I8T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I8T-query.scw PDB file : Tito_Scwrl_1I8T.pdb: