Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLVFVCLGNICRSPMAEFVMKSMTD------NYEIQSRATSSWEHGNPIHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDKIYSFS----SESVPDPWYTG--DFEETYRRVQEGCQAWLERLEKES 2CWD Chain:B ((4-151)) PVRVLFVCLGNICRSPMAEGIFRKLLKERGLEDRFEVDSAGTGAWHVGEPMDPRARRVLEEEGAYFP--HVARRLTREDVLAYDHILVMDRENLEEVLRRFPE-ARGKVRLVLEELGGGEVQDPYYGDLEDFREVYWTLEAALQAFLDRHG---

General information: TITO was launched using: RESULT: Template: 2CWD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 690 1632 2.37 12.00 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : 2.37 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.633

(partial model without unconserved sides chains): PDB file : Tito_2CWD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CWD-query.scw PDB file : Tito_Scwrl_2CWD.pdb: