Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------MRDKIRLVSSAGTGYFYTTTKNKRTMPEKMEIKKFDPKIRQHVIFKEAKIK------- 4MYY Chain:A ((2-85)) SALEAKLLDEIKQSSNQELESSIDQILESIIN-----GGSMLNKFTKKEQILSEKQQIKQLSPLQRAALALKKLETKLNNTLHE

General information: TITO was launched using: RESULT: Template: 4MYY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 29 2875 99.12 62.49 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 99.12 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.197

(partial model without unconserved sides chains): PDB file : Tito_4MYY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MYY-query.scw PDB file : Tito_Scwrl_4MYY.pdb: