Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDRLQQFYIFTEVAKRQSFSEVANQLDLPRSTVTSAIQQLETHYGVRLFHRTTRKVSLTQDGQRILPECQNLLFDYEQLEQLIQTQKQHYRGTLKISMPSRIVHQVIIPELPDFYHRYPDIHLQLNSSDDLTDLIEKGIDCVVRVGELDNSSLIARFIGHLVMVNCASTQYLQDYGIPEQLNDLEQHKLINYAGAVGEKQGEFIYQGGTVM-MDSALSVNNTEAYIAAACA-GLGIIQLPYYDVQDKIEQGILVEVLSAYIAPSLPLNILYPNRSYIPKRLEVFMNWVGEVLNRKCIVIF 5X0O Chain:A ((7-201)) -------------------------------------------------------------------------------------------GKIKISTPYNLTKRMMMPMLNGFMSQYPEINIELTTESNADQLDPTEWDVIFRVGPQ--SSLIARKIGSVKDILVASPEYVNAHPMPTHAEDLHDHFLLK--GHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVMIKEYIADGSLVRILPDWSANPRDIYMLYN---HLPEKVRLFIDYV------------

General information: TITO was launched using: RESULT: Template: 5X0O.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 879 -90506 -102.96 -481.41 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -102.96 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_5X0O.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5X0O-query.scw PDB file : Tito_Scwrl_5X0O.pdb: