Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNQNNSPSDMGKIPLSDDKNLMNIAQYLKGVQQSHKRSIPPLE----QWHPKHCGKMDLTVKANGEW--WHEGQLIKRQALLDLFTKVLWKEEGKFYLKTPVEQIEIEVEDEPLLVNQVDQIEISGDEFLQLTTTNQDVILVDAEHPIFMREYAGELRPYVHVRFGINALIQRQAFYHLVNYGTLVENDKGETILQLKSGNLHLQLGT 5UDI Chain:A ((57-183)) --------------------NLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCE-EGWALL-------KCGGKNYERAKACFEKVLEVDPENPESSAGYA------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5UDI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 380 25902 68.16 214.06 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 68.16 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.025

(partial model without unconserved sides chains): PDB file : Tito_5UDI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5UDI-query.scw PDB file : Tito_Scwrl_5UDI.pdb: