Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKQTVQLEIISVNQTKTKIELVISQIEQQIKNRSLTPGTRLPSVRKLAKDLGFSVSTIVEAYERLIALGKIESRSGSGFYVVAPLAPLALNELGPKLDRSIDPLWISRQSLEAEPNAFKPGCGWLPN-DWMPLESIRKALRSATRSEDDSLLGYSSPLGLSALRDLLAR-RAQSKGIEANLNQVLLTDSGTQAIDLVCRFLLKPDDVVLIDDPCYFNFHALLKVHQVKVVGIPYTPNGPDLEAFKEAI-----EGYNPRLYITNSGIHNPTGATLSLSTAHQLLKLIDQSNLIVIEDDIFSDFEYT--PAPRLAALDNLSRVIFIGSFSKTLSASIRCGYIIAKPEWIDQIADLKIATSFSHNGLSAKILHTALTDGSY-RKHL----DLLKVRLAQAMQETIAKLKSIRIEPWIEPKAGIFVWCRLPEGVDAEKIAQFCLNRQVILAPGNAFSQAQSAGQFIRFNITQSNHDYIY---KTLAEALLQESLEKQV 3WX9 Chain:A ((82-445)) --------------------------------------------------------------------------------------------------------------------------AGGLPNPKTFPKEIIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKWLGKRYGISQD-NDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILAPGFRIGWMVGDPGIIRKMEIAKQSTDLCTN-VFGQVVAWRYVDGGYLEKHIPEIRKFYKPR-RDAMLEALEEFMPEGVK-WTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEE------

General information: TITO was launched using: RESULT: Template: 3WX9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1929 -18002 -9.33 -51.88 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -9.33 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.512

(partial model without unconserved sides chains): PDB file : Tito_3WX9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WX9-query.scw PDB file : Tito_Scwrl_3WX9.pdb: