Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAANKILLQKGFCAEMEKYTRYKELYMSLPLINKQFMKQGLAITIATMKMNVTHATTEPQEIQQLGTDLNALFFNEKEKGTDSRVMTMACYSL 1L5H Chain:B ((127-172)) ---------------------------------QQNMKDGLQNCKATYKPDMIAVSTTCMA-EVIGDDLNAFINNSKKEG-------------

General information: TITO was launched using: RESULT: Template: 1L5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 76 -545 -7.17 -11.85 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain B : 0.60 3D Compatibility (PKB) : -7.17 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.256

(partial model without unconserved sides chains): PDB file : Tito_1L5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L5H-query.scw PDB file : Tito_Scwrl_1L5H.pdb: