Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQ-HLLLADAQALTDNADNPDKVRRNILEVALDYLAVGIDPTKTTICVQSCLPALNELTMLYLNFVTVARLERNPT---IKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLLPECKALLSNMARLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQVEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPMRERREELAKDPDYIMDVLRQGTDKCRIITQQTLDEVKDGLGLFKF 2G36 Chain:A ((15-338)) ---------ILSGMRPTGKLHIGHLVGALENWVKLQEEGNECFYFVADWHALTTHYDDVSKLKEYTRDLVRGFLACGIDPEKSVIFVQSGVKEHAELALLFSMIVSVSRLERVPTYKEI-------DLS---TAGFLIYPVLQAADILIYKAEGVPVGEDQVYHIELTREIARRFN-YLYDEVFPEPEAILSRVPKLPGTDGR-KMSKSYGNIINLEISEKELEQTILRMMTDPARVRRSDPGNPENCPVWKYHQAFDISEEESKWVWEGCTTASIGCVDCKKLLLKNMKRKLAPIWENFRKIDEDPHYVDDVIMEGTKKAREVAAKTMEEVRRAMNL---

General information: TITO was launched using: RESULT: Template: 2G36.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1423 -26041 -18.30 -83.20 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -18.30 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.527

(partial model without unconserved sides chains): PDB file : Tito_2G36.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2G36-query.scw PDB file : Tito_Scwrl_2G36.pdb: