Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRKKEVVSGNFVKYDAVVLGSGPAGEGAAMKLAKAGKRVAIVDVRDQLGGNCAHVGTIPSKALRQTVSSIIRYQRDPMFQKVGEWKQFTMKQVLRNAHKVIQQQ---VDTHT----RFYDRNKIGVFHGRAYIQDKNTVLVFSHEGIKETIICKQIVIGTGSRPYHPQGLDFDHPRVFDSDKILDLDYSIQKIIIYGAGVIGCEYASIFIGLDHKVDLINTQQKLLSY-----LDDEIADALSYHLREQGVLIRHNEQMDHLETFDD---HVVLHLQSGKK---IKADAILWCNGRSGNTEGLGLENVGLVPNSRGQLSVNDQYQTEVENIYAAGDVIGWPSLASAAYDQGRCAGANMSGEDAK-PVRDIPTGIYTIPEISSIGKNEQELTEEKIPYEVGQASFRHLARAQITGDTVGELKILFHRDTLEILGIHCFGNNAAEIIHIGQAVMHSPNNTLKYFVETTFNYPTMAEAYRVAALNGMNRLF 1ZMD Chain:A ((5-464)) ------------IDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNN-SHYYHMAHGTDFASRG----IEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADV----TAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVN-EAALALEYGASCEDIARVCHAHPTLSEAFREANL-------

General information: TITO was launched using: RESULT: Template: 1ZMD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2568 -15461 -6.02 -35.06 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -6.02 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.422

(partial model without unconserved sides chains): PDB file : Tito_1ZMD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZMD-query.scw PDB file : Tito_Scwrl_1ZMD.pdb: