Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNMTRYVLELNKNIRTFLKMQLNPIYYNEQHIAFADNVRRFVQKEMTPFVNEWDEAETFPRELYKKAAEIGLLGLGFSEEYGGIPDADPFYSLLAGIEMAKAGSGGVHISLMVHTIGAPPIQHFGSEELKARVLPGIISGEKISALAITEPGGGSDVAALQTKAVRDGDYYIVSGEKTFITSGIRADYYTVAVRTDPTKTGA-EGISMLLIDAHSEGITKTPLKKMGWWASDTAHLHFDQVRVPASNLLG-KENAGFKVIMNNFNMERFFLGVVAYGYALVCYEEALEWVQQRKTFGKRLIDHQVVRHKLVDMATQLTSTRALLEETAWKMTQPKLQGPELVAQISMLKNVATRTMQFCADAAVQTLGGMGFMRGTKSERIYREVKVNMIGGGAEEIMKDLISKQLGY 4IV6 Chain:A ((17-380)) -------------------------------------TVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGFGAVSMPCYVQVAE-ELAR-GWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRATMALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKGVSILLVEKVPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLLLSAAEKFD----AGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLMIVGEGTNEIQRNVIAKQL--

General information: TITO was launched using: RESULT: Template: 4IV6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2034 -71763 -35.28 -198.24 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -35.28 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_4IV6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IV6-query.scw PDB file : Tito_Scwrl_4IV6.pdb: