Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAEEKLNLADAIKITEFGMKNMPTKIEIWK 2L1P Chain:A ((22-79)) ------VRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYA-NVSAAKCQEFGRWYKHFKKT------

General information: TITO was launched using: RESULT: Template: 2L1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 131 -20825 -158.97 -359.05 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -158.97 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.596

(partial model without unconserved sides chains): PDB file : Tito_2L1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2L1P-query.scw PDB file : Tito_Scwrl_2L1P.pdb: