Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTYSHIYQVLFLPKLSIKRWHFLGLVLVN---------FALSYLSHFELFMVQWKHVIQII 1UX6 Chain:A ((185-225)) ------------------AVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQ--

General information: TITO was launched using: RESULT: Template: 1UX6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 25 -5382 -215.28 -168.19 target 2D structure prediction score : 0.00 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -215.28 2D Compatibility (Sec. Struct. Predict.) : 0.00 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.110

(partial model without unconserved sides chains): PDB file : Tito_1UX6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UX6-query.scw PDB file : Tito_Scwrl_1UX6.pdb: