Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTMQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHIIGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILKLLKIQLIHCHGYSTNYFL--YMLKKLDKNGFGKVKTVITCHGW----VEYNLKKKFLTYFDFWTYSMGDAFICVSETMKKRLESIIK-NKKIVAINNGINVSNSDLDVV-GVQDFKKEFCIPNNKKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTSVLASNVGGLSEIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSHG 5D00 Chain:A ((90-377)) ------------------------------------------------------------------------------------------------------------LDIIHAH-YALPHAVCAYLAKQMLKRNIG---IVTTLHGTDITVLGYDPSLKDLIRFAIES---SDRVTAVSSALAAETYDLIKPEKKIETIYNFI----------KNTAAIKEKHGILPDEKVVIHVSNFRKVKRVQDVIRVFRNI-AGKTKAKLLLVGDGPEKSTACELIRKYGLEDQVLMLGNQDRVEDLYSISDLKLLLSEKESFGLVLLEAMACGVPCIGTNIGGIPEVIKNNVSGFLVDVGDVTAATARAMSILEDEQLSNRFTKAAIEMLENEFSSKKIVSQYEQIYADLAE-----

General information: TITO was launched using: RESULT: Template: 5D00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1435 -6315 -4.40 -23.13 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -4.40 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_5D00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D00-query.scw PDB file : Tito_Scwrl_5D00.pdb: