Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGIVDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAFKQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVEKFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDIMTNHINSGMSKMFESLLITLALGAGTSVALVLMN 1VP7 Chain:C ((23-50)) -------------------------------------------------------------------------------ALAELESLVSAMENGTLPLEQSLSAYRR-------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1VP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 31 -3402 -109.73 -121.48 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain C : 0.43 3D Compatibility (PKB) : -109.73 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.43 QMean score : 0.696

(partial model without unconserved sides chains): PDB file : Tito_1VP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VP7-query.scw PDB file : Tito_Scwrl_1VP7.pdb: