Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVYYPQPVDNLVNKRSCKRRRYITMKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEG--AQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSI------------------------GEADVSIRPGWFYHEDQDPK--SLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERPYEFATYRNELYKEDLALGAEVSGPALSADFDCRHLTDGLETSSWASDA-DLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEV-DGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKTPGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSRSSSSLEAKISIQPGTGVHGVAYQDEIYALAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS 3UES Chain:A ((19-477)) ----------------------------------PSSRQLAWQRMEMYAFLHFGMNTMTDREWGLGHEDPALFNPRNVDVDQWMDALVAGGMAGVILTCKHHDGFCLWPSRLTRHTVASSPWREGKGDLVREVSESARRHGLKFGVYLSPWDRTEESYGKGKA--YDDFYVGQLTELLT-----QYGPIFSVWLDGANGEGKNGKTQYYDWDRYYNVIRSLQPDAVI-SVCGPDVRWAGNEAGHVRDNEWSVVPRRLRSAELT-------------TTVSSQDDDLGSREAVAGYGDNVCWYPAEVDTSIRPGWFYHQSEDDKVMSADQLFDLWLSAVGGNSSLLLNIPPSPEGLLAEPDVQSLKGLGRRVSE-FREALA-SVRCEARTSSASAAAAHLVDGNRDTFWRPDADDAAPAITLTLPQPTTINAIVIEEAIEHGQRIEHLRVTGALPDGTERVLGQAGTVGYRRILRFDDVEVSSVTLHVDGSRLAPMISRAAAVR--------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3UES.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2250 -46343 -20.60 -111.40 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -20.60 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_3UES.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UES-query.scw PDB file : Tito_Scwrl_3UES.pdb: