Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIGQQRNILATLGIDVWIPRTQVCQKNNAHTLWRDQVVEPHESITVPTIDVPAFEQKNTQPQVFEIPKVVEEPPIVVAEVSQPEILVEKPKVIEQETITPFELQAYCLEKCVIFVDVTALETEEKQLWANIQKAKVGRYSE------LRWPFPLAAYQ-DQRGVGSYIQGFLDAV---AAEKKILCLGKCAYI----Q---------------HANIIHLASLKEMLDKPLL-----KKRLWQLMQDNNE 1UI0 Chain:A ((56-182)) -------------------------------------------------------------------------------------------------------------------------GKAGQLLNRILEAAGIPREEVYITNIVKCRP-PQNRAPLPDEAKICTDKWLLKQIELIAPQIIVPLGAVAAEFFLGEKVSITKVRGKWYEWHGIKVFPMFHPAYLLRNPSRAPGSPKHLTWLDIQEVK-

General information: TITO was launched using: RESULT: Template: 1UI0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 233 3636 15.61 39.10 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : 15.61 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.338

(partial model without unconserved sides chains): PDB file : Tito_1UI0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UI0-query.scw PDB file : Tito_Scwrl_1UI0.pdb: