Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAYSEKVIDHYENPRNVGVLDKNSENVGTGMVGAPACGDVMRLQIQVNDNGVIEEARFKTYGCGSAIASSSLVTEWLKGKTLDEAQAIKNIDIATELALPPVKVHCSVLAEDAIKAAIEDYRSKKSKA 1WFZ Chain:A ((8-121)) -----------ENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQ---

General information: TITO was launched using: RESULT: Template: 1WFZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 596 -39613 -66.46 -347.48 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.89 3D Compatibility (PKB) : -66.46 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.665

(partial model without unconserved sides chains): PDB file : Tito_1WFZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WFZ-query.scw PDB file : Tito_Scwrl_1WFZ.pdb: