Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMNKQPQNSALVVVDVQNGF-TPGGNLAVADADTIIPTINQLA----GCFENVVLTQDWHPDNHISFAANHPGKQPFETIEL------DYGSQ--VLWPKHCIQGTHDAEFHPDL--NIPTAQL-IIRKGFHAHIDSYSAFMEADHTTMTGLTGYLKERGIDTVYVVGIATDFCVAWTALDAVKQGFKTLVIEDACKGIDLNGSLEQAWQTMQQQGVIRIQSTDLLNEC 2H0R Chain:A ((2-192)) ---------KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTTVLLDYTRPI------------------------------

General information: TITO was launched using: RESULT: Template: 2H0R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 897 18476 20.60 105.58 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 20.60 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.503

(partial model without unconserved sides chains): PDB file : Tito_2H0R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H0R-query.scw PDB file : Tito_Scwrl_2H0R.pdb: