Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRSLKKGPFVDAHLFAKVEAAVASNSRKPIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTEHMVGHKLGEFAPTRTYRGHGVDKKSKR 5O5J Chain:S ((2-83)) -PRSLKKGPFVDDHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTEAMVGHKLGEFAPTRTFKGH--------

General information: TITO was launched using: RESULT: Template: 5O5J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain S - contact count / total energy / energy per contact / energy per residue : 287 -40071 -139.62 -488.67 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain S : 0.90 3D Compatibility (PKB) : -139.62 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.650

(partial model without unconserved sides chains): PDB file : Tito_5O5J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5O5J-query.scw PDB file : Tito_Scwrl_5O5J.pdb: